Microwave-assisted oxidation of indan-1-ones into ninhydrins. Issue 14 (1st April 2015)

• Record Type: Journal Article
• Authors: Marminon, Christelle; Nacereddine, Abdelhamid; Bouaziz, Zouhair; Nebois, Pascal; Jose, Joachim; Le Borgne, Marc
• Is Part Of: Tetrahedron letters. Volume 56:Issue 14(2015)
• Page Start: 1840
• Page End: 1842
• Publication Date: 2015-04-01
• Subjects: Ninhydrin -- Oxidation -- Microwave-assisted synthesis -- Indan-1-one -- Selenium dioxide; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.02.086
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: A simple and general microwave-assisted selenium oxidation has been developed for the synthesis of substituted ninhydrins from indan-1-ones in order to access to indeno[1, 2- b ]indoles substituted on the A ring. This efficient and convenient oxidation, using selenium dioxide under microwave irradiations, afforded mono- and di-substituted ninhydrins in a single step reaction with good yields.