Blastic plasmacytoid dendritic cell neoplasm. Issue 4 (4th March 2018)

• Record Type: Journal Article
• Authors: Rai, Manoj Ponadka; Bedi, Prabhjot Singh; Kandola, Samanjit Kaur; Kavuturu, Shilpa; Singhal, Rashi
• Is Part Of: Clinical case reports. Volume 6:Issue 4(2018)
• Page Start: 770
• Page End: 772
• Publication Date: 2018-03-04
• Subjects: Allogeneic hematopoietic stem cell transplantation (alloHSCT) -- blastic plasmacytoid dendritic cell neoplasm -- CD4, CD56 and CD123; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.1457
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Blastic plasmacytoid dendritic cell neoplasm is an aggressive neoplasm with a median survival of only a few months despite treatment. An exhaustive immunohistochemical workup is required to differentiate it from myeloid sarcoma and extranodal NK/T cell lymphoma. Treatment is with induction using a regimen utilized for leukemia. Allogeneic hematopoietic stem cell transplantation is recommended for those who achieve remission following induction. Abstract : Blastic plasmacytoid dendritic cell neoplasm is an aggressive neoplasm with a median survival of only a few months despite treatment. An exhaustive immunohistochemical workup is required to differentiate it from myeloid sarcoma and extranodal NK/T cell lymphoma. Treatment is with induction using a regimen utilized for leukemia. Allogeneic hematopoietic stem cell transplantation is recommended for those who achieve remission following induction.