Synthesis of dibenzo[b, d]furans through one-pot cascade reactions of 1-arylpenta-3, 4-dien-2-ones with activated ketones. Issue 12 (18th March 2015)

• Record Type: Journal Article
• Authors: He, Yan; Guo, Shenghai; Zhang, Xinying; Guo, Chenhao; Fan, Xuesen
• Is Part Of: Tetrahedron letters. Volume 56:Issue 12(2015)
• Page Start: 1513
• Page End: 1516
• Publication Date: 2015-03-18
• Subjects: 1-Arylpenta-3, 4-dien-2-ones -- Activated ketones -- Dibenzo[b, d]furans -- One-pot cascade reactions; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.01.179
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: One-pot cascade reaction of 1-arylpenta-3, 4-dien-2-ones with activated ketones including base-promoted Michael addition/intramolecular aldol condensation/copper-catalyzed C–H activation and annulation offers a simple and convenient approach toward dibenzo[ b, d ]furans. This reaction obviates highly functionalized starting materials and step by step operations and affords products with good efficiency and high sustainability.