Synthesis of isocyanides through dehydration of formamides using XtalFluor-E. Issue 2 (8th January 2015) - Keita, Massaba
Graphical abstract: Abstract: The formation of isocyanides from formamides using XtalFluor-E, [Et2 NSF2 ]BF4, is presented. A wide range of formamides can be used to produce the corresponding isocyanides in up to 99% yield. In a number of cases, the crude products showed good purity (generally >80% by NMR) allowing to be used directly in multi-component reactions.