Novel and highly efficient one pot protocol for the synthesis of diversely functionalized triarylmethanes. Issue 6 (4th February 2015)

• Record Type: Journal Article
• Authors: Babu, B. Madhu; Thakur, Pramod B.; Bangade, Vikas M.; Meshram, H.M.
• Is Part Of: Tetrahedron letters. Volume 56:Issue 6(2015)
• Page Start: 766
• Page End: 771
• Publication Date: 2015-02-04
• Subjects: Triarylmethanes -- Friedel–Crafts reaction -- Oxidation -- BF3·OEt2 -- Lewis acid; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2014.11.139
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: An efficient, convenient, and novel one pot approach is described for the synthesis of triarylmethanes by in situ oxidation of benzylalcohols followed by the Friedel–Crafts alkylation of di/trimethoxybenzenes in the presence of BF3 ·OEt2 . The generality of the present method is strengthened by screening a variety of aromatic, aliphatic, and heteroaromatic alcohols with methoxy arenes. Shorter reaction time, mild reaction condition, good yields, and wide scope of substrates are the significant features of this protocol.