Diversity-oriented synthesis of fused-imidazole derivatives via Groebke–Blackburn–Bienayme reaction: a review. Issue 2 (14th January 2015)

• Record Type: Journal Article
• Authors: Devi, Nisha; Rawal, Ravindra K.; Singh, Virender
• Is Part Of: Tetrahedron. Volume 71:Issue 2(2015)
• Page Start: 183
• Page End: 232
• Publication Date: 2015-01-14
• Subjects: Diversity-oriented synthesis -- Imidazoheterocyclic -- Groebke–Blackburn–Bienayme reaction -- Fused imidazole -- Lewis acid -- Ugi type; Ac acetyl -- Aq aqueous -- Ar aryl -- Bn benzyl -- Boc tert-butoxycarbonyl -- BDMS bromodimethylsulfonium bromide -- CDK cyclin-dependent kinase -- CNTs carbon nanotubes -- CPUD cationic polyurethane dispersions -- DABCO 1, 4-diazabicyclo[2.2.2]octane -- DBU 1, 8-diazabicyclo[5.4.0]undec-7-ene -- DCE 1, 2-dichloroethane -- DCM dichloromethane -- DDQ 2, 3-dichloro-5, 6-dicyanobenzoquinone -- DIC diisopropylcarbodiimide -- DIEA or DIPEA diisopropylethylamine -- DMF dimethylformamide -- DMSO dimethylsulfoxide -- dppf 1, 3-bis(diphenylphosphino)propane -- EGFR epidermal growth factor receptor -- equiv equivalent -- Et ethyl -- Fmoc fluorenylmethyloxycarbonyl -- GBB Groebke–Blackburn–Bienayme -- Gsk3b glycogen synthase kinase 3 beta -- HATU 2-(1H-7-azabenzotriazol-1-yl)-1, 1, 3, 3-tetramethyl uronium hexafluorophosphate methanaminium -- ILs ionic liquids -- i-Pr isopropyl -- 5-LO 5-lipoxygenase -- MAPK mitogen-activated protein kinase -- PGHS-2 prostaglandin G/H synthase 2 -- MCM Mobil Composition of Matter -- MCR multicomponent reactions -- Me methyl -- Mont. montmorillonite -- MP macroporous polystyrene -- MW microwave -- n normal -- PBBS poly (N-bromobenzene-1, 3-disulfonamide) -- PEG polyethylene glycol -- Pent pentyl -- Ph phenyl -- Pr propyl -- T3P propylphosphonic anhydride -- RCM ring-closing metathesis -- Rock2 Rho-associated protein kinase 2 -- SAR Structure–activity relationship -- STAT5 Signal Transducer and Activator of Transcription 5 -- TBAB tetrabutylammoniumbromide -- TBAF tetrabutylammoniumfluoride -- TBBDA N, N, N′, N′-tetrabromobenzene-1, 3-disulfonamide -- TBTU N, N, N′, N′-tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate -- tert-bu tertiarybutyl -- TFA trifluoroacetic acid -- THF tetrahydrofuran -- TLR7 toll-like receptor 7 -- TMEDA tetramethylethylenediamine -- TosMIC toluene-4-sulfonylmethyl isocyanide -- TMSCN trimethylsilylcyanide -- Ts tosyl or 4-toluenesulfonyl -- TsOH/p-TSA p-toluenesulfonic acid; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2014.10.032
• Languages: English
• ISSNs: 0040-4020

Abstract

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