Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes. Issue 18 (7th March 2018)

• Record Type: Journal Article
• Authors: Musiejuk, M.; Doroszuk, J.; Witt, D.
• Is Part Of: RSC advances. Volume 8:Issue 18(2018)
• Page Start: 9718
• Page End: 9722
• Publication Date: 2018-03-07
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c8ra00659h
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : We developed a simple and efficient method for the synthesis of functionalized unsymmetrical Z -alkenyl disulfanes under mild conditions in moderate to good yields. Abstract : We developed a simple and efficient method for the synthesis of functionalized unsymmetrical Z -alkenyl disulfanes under mild conditions in moderate to good yields. The designed method is based on the reaction of Z -alkenyl thiotosylates with thiols in the presence of base. The developed method allows the preparation of unsymmetrical Z -alkenyl disulfanes bearing additional hydroxy, carboxy, or amino functionalities.