A Schiff base receptor as a fluorescence turn-on sensor for Ni2+ ions in living cells and logic gate application. (26th January 2018)

• Record Type: Journal Article
• Authors: Vinoth Kumar, Gujuluva Gangatharan; Kesavan, Mookkandi Palsamy; Sankarganesh, Murugesan; Sakthipandi, Kathiresan; Rajesh, Jegathalaprathaban; Sivaraman, Gandhi
• Is Part Of: New journal of chemistry. Volume 42:Number 4(2018)
• Page Start: 2865
• Page End: 2873
• Publication Date: 2018-01-26
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c7nj03784h
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A new receptor (R) with easily available "off–on–off" colorimetric and fluorescent responses was synthesized and characterized using 1 H NMR, 13 C NMR, and ESI-MS studies. Abstract : A new receptor (R) with easily available "off–on–off" colorimetric and fluorescent responses was synthesized and characterized using 1 H NMR, 13 C NMR, and ESI-MS studies. It exhibited selective and sensitive detection towards Ni 2+ ion without having any interference from other tested metal ions. The changes in the obtained photophysical properties are due to the chelation-enhanced fluorescence effect (CHEF) caused by the ligand-to-metal charge transfer (LMCT) that occur after the addition of Ni 2+ to the receptor. Density functional theory (DFT) calculations have theoretically supported the changes in the examined absorption and fluorescence spectra. Moreover, the receptor could be successfully oriented with the molecular logic functions of OR, AND, NOR, and NOT gates. Furthermore, the receptor efficacy was studied by examining the changes in intracellular Ni 2+ in the HeLa cells. The receptor has been explored for a possible application in the real sample analysis and a test kit for the detection of Ni 2+ .