Nickel-catalyzed cross-coupling of aldehydes with aryl halides via hydrazone intermediates. Issue 14 (30th January 2018)

• Record Type: Journal Article
• Authors: Tang, Jianting; Lv, Leiyang; Dai, Xi-Jie; Li, Chen-Chen; Li, Lu; Li, Chao-Jun
• Is Part Of: Chemical communications. Volume 54:Issue 14(2018)
• Page Start: 1750
• Page End: 1753
• Publication Date: 2018-01-30
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc09290c
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A novel nickel-catalyzed cross-coupling reaction between aldehydes and aryl halides via hydrazone intermediates has been developed. It merges the Wolff–Kishner reduction and classical cross-coupling reactions, thus opening up new routes in designing chemical synthesis. Abstract : Traditional cross-couplings require stoichiometric organometallic reagents. A novel nickel-catalyzed cross-coupling reaction between aldehydes and aryl halides via hydrazone intermediates has been developed, merging the Wolff–Kishner reduction and the classical cross-coupling reactions. Aromatic aldehydes, aryl iodides and aryl bromides are especially effective in this new cross-coupling chemistry.