UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions. Issue 15 (23rd February 2018)

• Record Type: Journal Article
• Authors: Gelat, Fabien; Roger, Maxime; Penverne, Christophe; Mazzad, Ahmed; Rolando, Christian; Chausset-Boissarie, Laëtitia
• Is Part Of: RSC advances. Volume 8:Issue 15(2018)
• Page Start: 8385
• Page End: 8392
• Publication Date: 2018-02-23
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra12977g
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : In this study, we report an efficient UV-mediated hydrophosphinylation of unactivated alkenes with H -phosphinates and hypophosphorous acid under radical free conditions in batch and in continuous flow. Abstract : A UV-mediated hydrophosphinylation of unactivated alkenes with H -phosphinates and hypophosphorous acid under radical free conditions is presented. The reaction affords selectively a large number of structurally diverse organophosphorous compounds in moderate to good yields under mild reaction conditions in the presence of an organic sensitizer as catalyst irradiated by UV-A LEDs. Furthermore, the high yielding hydrophosphinylation in continuous flow is disclosed.