Construction of tunable peptide nucleic acid junctions. Issue 23 (24th January 2018)

• Record Type: Journal Article
• Authors: Duan, Tanghui; He, Liu; Tokura, Yu; Liu, Xin; Wu, Yuzhou; Shi, Zhengshuang
• Is Part Of: Chemical communications. Volume 54:Issue 23(2018)
• Page Start: 2846
• Page End: 2849
• Publication Date: 2018-01-24
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc00108a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : We report here the construction of 3-way and 4-way peptide nucleic acid (PNA) junctions as basic structural units for PNA nanostructuring. Abstract : We report here the construction of 3-way and 4-way peptide nucleic acid (PNA) junctions as basic structural units for PNA nanostructuring. The incorporation of amino acid residues into PNA chains makes PNA nanostructures with more structural complexity and architectural flexibility possible, as exemplified by building 3-way PNA junctions with tunable nanopores. Given that PNA nanostructures have good thermal and enzymatic stabilities, they are expected to have broad potential applications in biosensing, drug delivery and bioengineering.