Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe. Issue 15 (31st January 2018)
- Record Type:
- Journal Article
- Title:
- Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe. Issue 15 (31st January 2018)
- Main Title:
- Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe
- Authors:
- Ali, Firoj
Aute, Sunil
Sreedharan, Sreejesh
Anila, H. A.
Saeed, Hiwa K.
Smythe, Carl G.
Thomas, Jim A.
Das, Amitava - Abstract:
- Abstract : A probe that specifically images HOCl in Golgi apparatus and lysosomes that is compatible wih the super resolution microscopy technique, SIM, is reported. Abstract : BODIPY derivative, SF-1, exclusively shows a fluorescence ON response to HOCl and images endogenously generated HOCl in RAW 264.7 macrophages. Widefield and super resolution structured illumination microscopy images confirm localization in the Golgi complex and lysosomes, and hence specifically detects HOCl generated in these organelles.SF-1 is compatible with 3D-SIM imaging of individual cells.
- Is Part Of:
- Chemical communications. Volume 54:Issue 15(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 15(2018)
- Issue Display:
- Volume 54, Issue 15 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 15
- Issue Sort Value:
- 2018-0054-0015-0000
- Page Start:
- 1849
- Page End:
- 1852
- Publication Date:
- 2018-01-31
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc09433g ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6181.xml