The spectrum of bleeding in women and girls with haemophilia B. Issue 2 (27th November 2017)

• Record Type: Journal Article
• Authors: Staber, J.; Croteau, S. E.; Davis, J.; Grabowski, E. F.; Kouides, P.; Sidonio, R. F.
• Is Part Of: Haemophilia. Volume 24:Issue 2(2018)
• Page Start: 180
• Page End: 185
• Publication Date: 2017-11-27
• Subjects: haemophilia -- haemophilia carriers -- review -- women with bleeding disorders; Hemophilia -- Periodicals; 616.1572005
• DOI: 10.1111/hae.13376
• Languages: English
• ISSNs: 1351-8216

Abstract

Abstract : Although hemophilia B affects 1 in 25, 000 males there may be 3 female hemophilia B carriers per affected male. This clinical review highlights the unique challenges faced by hemophilia B carriers including the under‐recognition of bleeding symptoms associated with and without FIX deficiency, discrepancies in correlation between genotype and bleeding phenotype and therapeutic considerations utilizing clinical vignettes of common scenarios.