Supramolecular protein cages constructed from a crystalline protein matrix. Issue 16 (6th February 2018)

• Record Type: Journal Article
• Authors: Negishi, Hashiru; Abe, Satoshi; Yamashita, Keitaro; Hirata, Kunio; Niwase, Kento; Boudes, Marion; Coulibaly, Fasséli; Mori, Hajime; Ueno, Takafumi
• Is Part Of: Chemical communications. Volume 54:Issue 16(2018)
• Page Start: 1988
• Page End: 1991
• Publication Date: 2018-02-06
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc08689j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Protein cages were constructed by cross-linking monomers in polyhedra crystals, followed by dissolution of the crystals. Abstract : Protein crystals are formed via ordered arrangements of proteins, which assemble to form supramolecular structures. Here, we show a method for the assembly of supramolecular protein cages within a crystalline environment. The cages are stabilized by covalent cross-linking allowing their release via dissolution of the crystal. The high stability of the desiccated protein crystals allows cages to be constructed.