How does the surface treatment change the cytocompatibility of implants made by selective laser melting?. (3rd April 2018)

• Record Type: Journal Article
• Authors: Matouskova, Lucie; Ackermann, Michal; Horakova, Jana; Capek, Lukas; Henys, Petr; Safka, Jiri
• Is Part Of: Expert review of medical devices. Volume 15:Number 4(2018)
• Page Start: 313
• Page End: 321
• Publication Date: 2018-04-03
• Subjects: Selective laser melting -- Ti6Al4V -- individual medical implants -- surface roughness -- in vitro testing; Medical instruments and apparatus -- Periodicals; 610.28
• DOI: 10.1080/17434440.2018.1456335
• Languages: English
• ISSNs: 1743-4440

Abstract

ABSTRACT: Introduction : The study investigates the potential for producing medical components via Selective Laser Melting technology (SLM). The material tested consisted of the biocompatible titanium alloy Ti6Al4V. The research involved the testing of laboratory specimens produced using SLM technology both in vitro and for surface roughness. The aim of the research was to clarify whether SLM technology affects the cytocompatibility of implants and, thus, whether SLM implants provide suitable candidates for medical use following zero or minimum post-fabrication treatment. Areas covered : The specimens were tested with an osteoblast cell line and, subsequently, two post-treatment processes were compared: non-treated (as-fabricated) and glass-blasted. Interactions with MG-63 cells were evaluated by means of metabolic MTT assay and microscope techniques (scanning electron microscopy, fluorescence microscopy). Surface roughness was observed on both the non-treated and glass-blasted SLM specimens. Expert Commentary : The research concluded that the glass-blasting of SLM Ti6Al4V significantly reduces surface roughness. The arithmetic mean roughness Ra was calculated at 3.4 µm for the glass-blasted and 13.3 µm for the non-treated surfaces. However, the results of in vitro testing revealed that the non-treated surface was better suited to cell growth.