Gem-Diborylalkanes: recent advances in their preparation, transformation and application. Issue 7 (30th January 2018)

• Record Type: Journal Article
• Authors: Nallagonda, Rajender; Padala, Kishor; Masarwa, Ahmad
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 7(2018)
• Page Start: 1050
• Page End: 1064
• Publication Date: 2018-01-30
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob02978k
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Recently, gem -diborylalkanes have attracted much attention as versatile building blocks and fundamental intermediates in organic synthesis, because they enable multiple C–C bond construction and further transformation at C–B bonds. Abstract : Recently, gem -diborylalkanes have attracted much attention as versatile building blocks and fundamental intermediates in organic synthesis, because they enable multiple C–C bond construction and further transformation at C–B bonds. Importantly, gem -diborylalkanes can be utilised as bisnucleophilic partners in a variety of chemo -selective C–C bond-forming reactions. This review describes recent developments in synthesising gem -diborylalkanes in complex molecules along with their chemical transformation. In the first part of the review the different synthetic approaches used to synthesise gem -diborylalkanes are described. In the second part, an overview of the chemoselective transformation of gem -diborylalkanes into various functionalized materials is discussed along with one-carbon homologation of diborylmethane via a selective uni- and bidirectional method.