Systemic lupus erythematosus complicated with liver cirrhosis in a patient with Papillon-Lefèvre syndrome. (December 2014)

• Record Type: Journal Article
• Authors: Yasudo, H; Ando, T; Takeuchi, M; Nakano, H; Itonaga, T; Takehara, H; Isojima, T; Miura, K; Harita, Y; Takita, J; Oka, A
• Is Part Of: Lupus. Volume 23:Number 14(2014)
• Page Start: 1523
• Page End: 1527
• Publication Date: 2014-12
• Subjects: Cirrhosis -- Papillon-Lefèvre syndrome -- systemic lupus erythematosus; Systemic lupus erythematosus -- Periodicals; 616.772005
• DOI: 10.1177/0961203314547794
• Languages: English
• ISSNs: 0961-2033

Abstract

We report the first case of a girl who presented with Papillon-Lefèvre syndrome (PLS) and subsequently developed systemic lupus erythematosus and liver cirrhosis. This indicates that autoimmune diseases can be a complication in patients with PLS. Cathepsin C gene mutations were not found in our patient or her mother. Thus, other genetic factors may have been involved in this patient.