PS 11-71 INFLUENCE OF BMI ON CARDIAC OUTPUT AND PERIPHERAL BLOOD FLOW IN YOUNG ADULT MALES. (September 2016) - Arora, Shitij
Abstract : Objective: To determine association between cardiac output and BMI in young adult males. To compare forearm blood flow & BMI in young adult males. To compare calf blood flow with BMI in young adult males. Design and Method: 90 males with age 17 -25 years & no H/o smoking and alcoholism, diabetes mellitus, hypertension, cardiovascular or respiratory diseases were enrolled after taking informed consent. BMI (kg/m2) was calculated by the Quitelet's formula: weight/ height 2 (kg/ m 2 ). Equal numbers of subjects were categorized into three groups according to BMI (South Asian Standards): Group A: Non obese (BMI < 22.9 Kg/m 2 ), Group B: Overweight (BMI between 23 to 24.9 Kg/m 2 ) and Group C: Obese (BMI ≥ 25 Kg/m 2 ) Cardiac output & peripheral blood flow of forearm and calf were measured using NIVOMON series – Non invasive Continuous Cardiac Output & Peripheral Blood Flow Monitor. One Way ANOVA was done to compare Cardaic output & Peripheral blood flow with different BMI groups. Results: Cardiac output was significantly more in obese group compared to overweight and normal BMI group [5.7 +/- 0.43 vs 5.26 +/- 0.54 vs 4.95 +/- 0.65 L/min, P<0.01). Forearm and calf blood flow (assessed by blood flow index) of both limbs were significantly less in obese group compared to overweight and normal (P < 0.01). Conclusions: Obese subjects have increased cardiac output as compared to subjects who were overweight and have normal BMI. If they continue to be obese, they may land up with cardiac complications like left ventricular hypertrophy and high output cardiac failure in years to come. Moreover the peripheral blood has decreased in these obese subjects which shows endothelial dysfunction and accelerated atherosclerotic changes in the form of vasoconstriction which may result in peripheral artery disease in future. So reducing obesity is the need of the hour.