Continuous Spike and Wave in Slow-Wave Sleep in a Patient With Rett Syndrome and in a Patient With Lhermitte-Duclos Syndrome and Neurofibromatosis 1. (December 2014)

• Record Type: Journal Article
• Authors: Bhat, Sushanth; Ming, Xue; Dekermenjian, Rony; Chokroverty, Sudhansu
• Is Part Of: Journal of child neurology. Volume 29:Number 12(2014:Dec.)
• Page Start: NP176
• Page End: NP180
• Publication Date: 2014-12
• Subjects: continuous spike and wave in slow-wave sleep -- CSWS -- Rett syndrome -- Lhermitte-Duclos syndrome -- Cowden disease; Nervous system -- Diseases -- Periodicals; 618.928
• DOI: 10.1177/0883073813509888
• Languages: English
• ISSNs: 0883-0738

Abstract

Continuous spike and wave in slow-wave sleep (CSWS) is an electroencephalographic (EEG) pattern characterized by generalized spike-wave discharges occurring for at least 85% of non–rapid eye movement (non-REM) sleep, with marked attenuation during rapid eye movement (REM) sleep. It has been described in a large number of structural and nonstructural neurologic conditions and is associated with epilepsy, behavioral disturbances, and severe neuropsychiatric impairment. We describe continuous spike and wave in slow-wave sleep in 2 patients (one with Rett syndrome and the other with Lhermitte-Duclos syndrome). To our knowledge, continuous spike and wave in slow-wave sleep has not been previously described in these conditions.