Biodegradable Cell-Seeded Collagen Based Polymer Scaffolds for Wound Healing and Skin Reconstruction. Issue 2 (1st February 2018)

• Record Type: Journal Article
• Authors: Ansari, Mojtaba; Kordestani, Soheila Salahshoor; Nazralizadeh, Sanaz; Eslami, Hossein
• Is Part Of: Journal of macromolecular science. Volume 57:Issue 2(2018)
• Page Start: 100
• Page End: 109
• Publication Date: 2018-02-01
• Subjects: Amniotic fluid-derived stem (AFS) cells -- collagen-glycosaminoglycan scaffolds -- extracellular matrix -- wound dressings -- wound healing; Polymerization -- Periodicals; Polymers -- Periodicals; 530.413
• DOI: 10.1080/00222348.2018.1435617
• Languages: English
• ISSNs: 0022-2348

Abstract

ABSTRACT: In the present study a collagen-glycosaminoglycans scaffold, following chemical modifications, was prepared as an analog of the extracellular matrix (ECM) by a freeze drying method. Appropriate tests related to its use for wound healing (evaluation of the structure by scanning electron microscopy, swelling properties, biodegradability properties, Fourier transform infrared spectroscopy and cell culture) were done on the scaffolds. Amniotic fluid-derived stem (AFS) cell seeded scaffolds were shown to be potentially useful for wound healing.