Two new iridoid glycosides from the leaves of Callicarpa nudiflora. Issue 3 (4th March 2018)

• Record Type: Journal Article
• Authors: Wang, Jie; Fu, Hui-Zheng; Luo, Yue-Hua; Ma, Yuan-Yu; Huang, Bo; Ma, Shuang-Cheng
• Is Part Of: Journal of Asian natural products research. Volume 20:Issue 3(2018)
• Page Start: 242
• Page End: 248
• Publication Date: 2018-03-04
• Subjects: Verbenacase -- Callicarpa nudiflora -- iridoid glycosides -- hepatoprotective activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2017.1323884
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Two new iridoid glycosides, callicoside C (1 ) and callicoside D (2 ), together with three known compounds (3 –5 ), were isolated from the leaves of Callicarpa nudiflora . Their structures were established by 1D and 2D NMR spectroscopy and mass spectrometry. In an in vitro bioassay, compound1 showed pronounced hepatoprotective activity againstd -galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells. Abstract :