Two pairs of unusual melibiose and raffinose esters from Scrophularia ningpoensis. Issue 3 (4th March 2018)

• Record Type: Journal Article
• Authors: Zhang, Jun; Liang, Yan; Ip, Fanny C. F.; Ip, Nancy Y.; Liu, Ting-Ting; Zhong, Ba-Lian; Xu, Shi-Hai
• Is Part Of: Journal of Asian natural products research. Volume 20:Issue 3(2018)
• Page Start: 255
• Page End: 262
• Publication Date: 2018-03-04
• Subjects: Scrophulariaceae -- Scrophularia ningpoensis -- phenylpropanoid glycoside -- melibiose ester -- raffinose ester; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2017.1329301
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: A pair of unusual melibiose esters (1 α /1 β ) and a pair of unusual raffinose esters (2 α /2 β ), were isolated from Scrophularia ningpoensis . Structures of them were established by detailed spectroscopic analyses to be 6- O -( E )-cinnamoyl- α -d -galactopyranosyl-(1→6)- α ( β )-d -glucopyranose (1 α /1 β ) and 6- O -( E )/( Z )-cinnamoyl- α -d -galactopyranosyl-(1→6)- α -d -glucopyranosyl-(1→2)- β -d -fructofuranose (2 α /2 β ), respectively. All these compounds were evaluated for antifouling activity against the settlement of Balanus amphitrite larvae, along with the cytotoxic effect against the proliferation of HeLa cell lines. Graphical abstract: