Synchronous Hodgkin lymphoma and gastric adenocarcinoma: A rare case report and literature review. Issue 3 (January 2018)

• Record Type: Journal Article
• Authors: Wu, Hongying; Wei, Liyan; Hao, Lumei; Li, Xuemei; Wang, Lei; Yuan, Chenglu
• Other Names: Alkhiary. Wael section editor.
• Is Part Of: Medicine. Volume 97:Issue 3(2018)
• Publication Date: 2018-01
• Subjects: adenocarcinoma -- gastric -- Hodgkin lymphoma -- synchronous; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000009484
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : Abstract: Hodgkin lymphoma (HL) is a lymphoproliferative disease arising in the lymphoid tissue, which is characterized by Reed–Sternberg cells. Adenocarcinoma is the most frequent pathological type of stomach cancer. Improved survival in HL patients leads to the development of secondary malignancies. However, synchronous occurrence of these 2 malignancies is extremely rare. Here, we present a 45-year-old male complaining of a lymph node mass in the neck, without any abdominal symptoms, diagnosed as HL and gastric adenocarcinoma with hepatitis B carrier status. We treated the patient with 8 courses of pirarubicin bleomycin, vincristine, and dacarbazine (modified ABVD), and 4 courses of capecitabine therapy concurrently along with oral entecavir, as the patient survived longer than 20 months. The prognosis of multiple primary malignancies is poor because therapy is difficult, without a standard treatment. The frequency of multiple primary malignancies is increasing in recent years, and second malignancies in patients with cancer should be taken into consideration.