Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma. Issue 50 (December 2017)

• Record Type: Journal Article
• Authors: Sun, Linge; Zhang, Lei; Hu, Wenlu; Li, Tian-Fang; Liu, Shengyun
• Other Names: Lipsker. Dan section editor.
• Is Part Of: Medicine. Volume 96:Issue 50(2017)
• Publication Date: 2017-12
• Subjects: amyloidosis -- myeloma -- scleroderma; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000008771
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Introduction: Amyloid light chain (AL) results from the deposition of immunoglobulin light chain fragments, and can affect multiple organs/systems. Our patient was diagnosed as scleroderma repeatedly because of extensive skin thickening and hardening, but the treatment was not effective. We did extensive laboratory examinations including serum/urine protein electrophoresis and flow cytometry assay of bone marrow aspiration. Conclusion: A diagnosis of primary AL amyloidosis was established.