The history and basic science development of soy isoflavones. Issue 12 (December 2017)

• Record Type: Journal Article
• Authors: Setchell, Kenneth D.R.
• Is Part Of: Menopause. Volume 24:Issue 12(2017)
• Publication Date: 2017-12
• Subjects: Equol -- Genistein -- Isoflavones -- Menopause -- Phytoestrogens -- Soy; Menopause -- Periodicals; 618.175005
• DOI: 10.1097/GME.0000000000001018
• Languages: English
• ISSNs: 1072-3714

Abstract

Abstract : Abstract: This review summarizes the 2016 NAMS/Pfizer—Wulf H. Utian Endowed Lecture that focused on the history and basic science of soy isoflavones. Described is a personal perspective of the background and history that led to the current interest in soy and isoflavones with a specific focus on the role that soy isoflavones play in the health of postmenopausal women. This overview covers the metabolism and physiological behavior of isoflavones, their biological properties that are of potential relevance to aging, issues related to the safety of soy isoflavones, and the role of the important intestinally derived metabolite S -(−)equol.