Dural Venous Sinus Thrombosis and Pulmonary Embolism Following Immunoglobulin Treatment in Pediatric Patient With Immune Thrombocytopenic Purpura. Issue 8 (November 2017)

• Record Type: Journal Article
• Authors: Park, Kyung Mi; Yang, Eu Jeen; Lim, Young Tak
• Is Part Of: Journal of pediatric hematology/oncology. Volume 39:Issue 8(2017)
• Publication Date: 2017-11
• Subjects: thrombosis -- intravenous immunoglobulin -- pediatric immune thrombocytopenic purpura; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000000841
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Intravenous immunoglobulin (IVIG) is a widely used agent as the first choice of treatment of immune thrombocytopenic purpura (ITP). IVIG has several side effects, but it is a relatively safe treatment. Life-threatening thrombosis has been reported in adults and rarely in children. We report a case of a 14-year-old boy with dural venous sinus thrombosis and pulmonary embolism after treatment with IVIG for ITP. The patient was treated with low–molecular-weight heparin followed by warfarin and the symptoms were recovered. If a patient with ITP shows mental change or respiratory difficulty, we should consider thrombosis as well as hemorrhage.