MRNA 3′ Uridylation and Poly(A) Tail Length Sculpt the Mammalian Maternal Transcriptome. Issue 11 (November 2017)

• Record Type: Journal Article
• Authors: Morgan, Marcos; Much, Christian; DiGiacomo, Monica; Azzi, Chiara; Ivanova, Ivayla; Vitsios, Dimitrios M.; Pistolic, Jelena; Collier, Paul; Moreira, Pedro N.; Benes, Vladimir; Enright, Anton J.; O'Carroll, Dónal
• Is Part Of: Obstetrical & gynecological survey. Volume 72:Issue 11(2017)
• Publication Date: 2017-11
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/OGX.0000000000000499
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Nature 2017;548:347–351) Gene expression in the early stages of zygotic development is characterized by a lack of transcription and is dependent on the maternally deposited transcriptome. The competence of the mature oocyte, upon ovulation, to support fertilization and development is largely defined by the maternal transcriptome.