Rh‐Catalyzed Annulation of ortho‐C−H Bonds of 2‐Arylimidazoles with 1, 4, 2‐Dioxazol‐5‐ones toward 5‐Arylimidazo[1, 2‐c]quinazolines. Issue 6 (17th January 2018)

• Record Type: Journal Article
• Authors: Wu, Xiaopeng; Sun, Song; Xu, Shengbo; Cheng, Jiang
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 6(2018)
• Page Start: 1111
• Page End: 1115
• Publication Date: 2018-01-17
• Subjects: Rhodium catalysis -- amidation -- annulation -- dioxazolones -- quinazolines; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201701331
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A Rh‐catalyzed unique and direct approach for constructing a series of 5‐arylimidazo[1, 2‐ c ]quinazolines in moderate to excellent yields from simple and readily available 2‐arylimidazoles and 3‐phenyl‐1, 4, 2‐dioxazol‐5‐ones was described. This procedure proceeds with sequential ortho ‐C−H bond amidation and cyclization, which represents a facile and straightforward pathway to access such frameworks. Abstract :