Assessment of the performance of small field of view gamma cameras for sentinel node imaging. Issue 11 (November 2015)
- Record Type:
- Journal Article
- Title:
- Assessment of the performance of small field of view gamma cameras for sentinel node imaging. Issue 11 (November 2015)
- Main Title:
- Assessment of the performance of small field of view gamma cameras for sentinel node imaging
- Authors:
- Ng, Aik Hao
Clay, David
Blackshaw, Patricia E.
Bugby, Sarah L.
Morgan, Paul S.
Lees, John E.
Perkins, Alan C. - Abstract:
- Abstract : Objective: To develop a method for the assessment of small field of view (SFOV) gamma cameras using a novel phantom designed to simulate the localization of sentinel nodes in the presence of a high-activity injection site. Materials and methods: The phantom consisted of a cube-shaped acrylic glass support frame. Sixteen acrylic glass plates and nine bars were stacked within the frame to allow a variable configuration of the simulated node depth and node-to-injection site separation. Syringes filled with 99m Tc were used to simulate activity at the injection site and node. Scintigraphic imaging was carried out and the images were assessed subjectively and quantitatively through calculation of the contrast-to-noise ratio. The detection performance of an SFOV gamma camera was then compared with that of a large field of view gamma camera. Results: The detectability studies showed that the SFOV gamma camera could detect low activity in nodes by visual examination of images and with contrast-to-noise ratios ranging from 3 to 62. In particular, the phantom showed the limits of node detection using an SFOV gamma camera over activity ratios less than 1 : 100 and at depths below 45 mm with 25 mm of node-to-injection site separation. Visual subjective assessment of images acquired under the same conditions showed that the SFOV gamma camera was superior to a large field of view camera for the detection of nodes at a node-to-injection site separation of 25 mm. Conclusion: AAbstract : Objective: To develop a method for the assessment of small field of view (SFOV) gamma cameras using a novel phantom designed to simulate the localization of sentinel nodes in the presence of a high-activity injection site. Materials and methods: The phantom consisted of a cube-shaped acrylic glass support frame. Sixteen acrylic glass plates and nine bars were stacked within the frame to allow a variable configuration of the simulated node depth and node-to-injection site separation. Syringes filled with 99m Tc were used to simulate activity at the injection site and node. Scintigraphic imaging was carried out and the images were assessed subjectively and quantitatively through calculation of the contrast-to-noise ratio. The detection performance of an SFOV gamma camera was then compared with that of a large field of view gamma camera. Results: The detectability studies showed that the SFOV gamma camera could detect low activity in nodes by visual examination of images and with contrast-to-noise ratios ranging from 3 to 62. In particular, the phantom showed the limits of node detection using an SFOV gamma camera over activity ratios less than 1 : 100 and at depths below 45 mm with 25 mm of node-to-injection site separation. Visual subjective assessment of images acquired under the same conditions showed that the SFOV gamma camera was superior to a large field of view camera for the detection of nodes at a node-to-injection site separation of 25 mm. Conclusion: A low-cost phantom has been designed and fabricated that provides a versatile method for the assessment of SFOV gamma cameras intended for sentinel node imaging. … (more)
- Is Part Of:
- Nuclear medicine communications. Volume 36:Issue 11(2015:Nov.)
- Journal:
- Nuclear medicine communications
- Issue:
- Volume 36:Issue 11(2015:Nov.)
- Issue Display:
- Volume 36, Issue 11 (2015)
- Year:
- 2015
- Volume:
- 36
- Issue:
- 11
- Issue Sort Value:
- 2015-0036-0011-0000
- Page Start:
- Page End:
- Publication Date:
- 2015-11
- Subjects:
- detectability -- intraoperative imaging -- sentinel lymph node biopsy -- sentinel node phantom -- small field of view gamma camera
Nuclear medicine -- Periodicals
616.07575 - Journal URLs:
- http://journals.lww.com/nuclearmedicinecomm/pages/default.aspx ↗
http://journals.lww.com/pages/default.aspx ↗
http://www.lww.com/Product/0143-3636 ↗ - DOI:
- 10.1097/MNM.0000000000000377 ↗
- Languages:
- English
- ISSNs:
- 0143-3636
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6180.923000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6062.xml