Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report. Issue 45 (November 2017)

• Record Type: Journal Article
• Authors: Xia, Nian-ge; Chen, Yan-yan; Wang, Xin-shi; Xu, Hui-qin; Zheng, Rong-yuan
• Other Names: Talele. Nilesh section editor.
• Is Part Of: Medicine. Volume 96:Issue 45(2017)
• Publication Date: 2017-11
• Subjects: adenoid cystic carcinoma -- cranial nerves palsy -- Garcin syndrome -- parotid gland -- PGACC; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000008508
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. Patient concerns: We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years. Diagnosis: A left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis. Interventions: The patient was treated 3 times with local-field palliative radiotherapy. Outcomes: She died after several months. Lessons: To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome.