Bone Regeneration of Macropore Octacalcium Phosphate–Coated Deproteinized Bovine Bone Materials in Sinus Augmentation: A Prospective Pilot Study. Issue 3 (June 2015)

• Record Type: Journal Article
• Authors: Lee, Jee-Ho; Kim, Jin-Hong; Jeon, Ju-Hong
• Is Part Of: Implant dentistry. Volume 24:Issue 3(2015:Jun.)
• Publication Date: 2015-06
• Subjects: sinus augmentation -- octacalcium phosphate -- macropore -- bovine bone; Dental implants -- Periodicals; 617.69305
• DOI: 10.1097/ID.0000000000000249
• Languages: English
• ISSNs: 1056-6163

Abstract

Abstract : Objective: To investigate the osteogenic potential of macropore octacalcium phosphate (OCP)–coated deproteinized bovine bone materials (DBBMs) in sinus augmentation. Study design: Macropore OCP-coated DBBM was manufactured from bovine bone by thermal and chemical processing. Sinus grafts of a lateral window approach with experimental bone were conducted in 10 patients. At 6 months after surgery, a total of 10 specimens were obtained from 10 patients. But, 4 of them were excluded because the amount of specimens was not enough for evaluation. Morphological investigation under scanning electron microscopy and histological evaluation were performed. Results: OCP was evenly attached to the surface of the experimental graft and showed a relatively large pore size (300–400 μm) compared with Bio-Oss (100–200 μm). New bone comprised 23.49% (±0.10), and residual graft material comprised 15.39% (±0.06) in bone specimens. Conclusion: A macropore-sized design and OCP coating could present a favorable environment for new bone formation in maxillary sinus grafts.