PET/CT Findings in a Case With FDG-Avid Disseminated Lacrimal Gland MALToma With Sequential Development of Large B-Cell Lymphoma and Gastric MALToma. (February 2015)

• Record Type: Journal Article
• Authors: Yildirim-Poyraz, Nilufer; Ozdemir, Elif; Basturk, Abdulkadir; Kilicarslan, Aydan; Turkolmez, Seyda
• Is Part Of: Clinical nuclear medicine. Volume 40:Number 2(2015)
• Publication Date: 2015-02
• Subjects: MALT lymphoma -- lacrimal gland -- diffuse large B-cell lymphoma -- 18F-FDG PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000000468
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Primary orbital lymphomas are rare; the major histopathologic type is extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) or MALToma. We present a case of a 79-year-old female patient with FDG-avid lacrimal gland MALToma with nodal and pulmonary involvement (stage IVE). Nasopharynx and gastric involvement were detected on restaging 18 F-FDG PET/CT after rituximab therapy, and it was found to have a site of transformation to diffuse large B-cell lymphoma (DLBCL) in the nasopharynx. Gastric MALT lymphoma was also confirmed histopathologically, and she then underwent combination chemotherapy regimen, resulting in regression after 3 courses.