Increased MIBG Activity in the Uterine Cervix Due to Menstruation. (February 2015)

• Record Type: Journal Article
• Authors: Liu, Bin; Yang, Hua; Codreanu, Ion; Zhuang, Hongming
• Is Part Of: Clinical nuclear medicine. Volume 40:Number 2(2015)
• Publication Date: 2015-02
• Subjects: MIBG -- ganglioneuroblastoma -- uterus -- menstruation -- false positive; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000000575
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 21-year-old woman with history of presacral ganglioneuroblastoma underwent 123 I-MIBG scan for restaging. Planar images revealed increased MIBG activity in the upper pelvis, suggestive of disease recurrence. Complementary SPECT/CT images, however, localized the activity to the uterine cervix. Upon further questioning, it has been established that the patient was menstruating. Subsequent follow-up scans proved normal, confirming the benign etiology of these findings. The case shows that radioactive blood accumulation in the uterine cervix can interfere with MIBG scan interpretation in menstruating patients.