Enhanced glucose sensing based on a novel composite CoII-MOF/Acb modified electrode. Issue 11 (16th February 2018)

• Record Type: Journal Article
• Authors: Wen, Yuanyuan; Meng, Wei; Li, Chen; Dai, Lei; He, Zhangxing; Wang, Ling; Li, Ming; Zhu, Jing
• Is Part Of: Dalton transactions. Volume 47:Issue 11(2018)
• Page Start: 3872
• Page End: 3879
• Publication Date: 2018-02-16
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c8dt00296g
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : A novel electrochemical sensor composed of a composite of Co II -MOF/acetylene black exhibits enhanced sensing behavior for glucose detection. Abstract : In this work, we demonstrate the synthesis and application of a novel Co II -based metal–organic framework {[Co2 (Dcpp)(Bpe)0.5 (H2 O)(μ2 -H2 O)]·(Bpe)0.5 } n (Co II -MOF, H4 Dcpp = 4, 5-bis(4′-carboxylphenyl)-phthalic acid, Bpe = 1, 2-bis(4-pyridyl)ethane) as an electrochemical sensor for glucose detection. Single-crystal X-ray diffraction analysis shows that the Co II -MOF has a two-dimensional (2D) bilayer structure composed of Co2 units and Dcpp 4− ligands. There are two kinds of Bpe in the structure: one serves as a bidentate ligand linking two Co1 atoms in each 2D layer; the other is just free in the lattice. The Co II -MOF modified glassy carbon electrode (GCE) shows good electrocatalytic activity towards glucose oxidation. To further improve the catalytic activity of the electrode, a new composite of Co II -MOF/acetylene black (Co II -MOF/Acb) was constructed. The Co II -MOF/Acb modified electrode exhibits enhanced sensing behavior for glucose detection. The sensing performance of Co II -MOF/Acb/GCE with different Acb loadings was investigated in detail. The results demonstrate that Co II -MOF/GCE with 2% Acb (Co II -MOF/Acb-2%/GCE) exhibits the best sensing behavior, including a high sensitivity of 0.255 μA μM −1 cm −2 and a wide linear range of 5–1000 μM, as well as a low detection limit of 1.7 μM (S/N = 3). It's worth noting that the linear range of Co II -MOF/Acb-2%/GCE was extended by more than ten times when compared to that of Co II -MOF/GCE without Acb addition. In addition, Co II -MOF/Acb-2%/GCE shows good selectivity and stability in the sensing process.