Thermo-responsive recoverable polymeric inhibitors for the resolution of racemic amino acids. Issue 22 (27th February 2018)

• Record Type: Journal Article
• Authors: Ye, Xichong; Zhang, Jie; Cui, Jiaxi; Wan, Xinhua
• Is Part Of: Chemical communications. Volume 54:Issue 22(2018)
• Page Start: 2785
• Page End: 2787
• Publication Date: 2018-02-27
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc00333e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Thermoresponsive polymeric inhibitors efficiently mediate the stereoselective crystallization of asparagine monohydrate and can be recollected by simply elevating the temperature. Abstract : Novel polymeric inhibitors with lower critical solution temperatures in water were prepared and used to mediate the crystallization of racemic asparagine monohydrate, leading to chiral separation with 88.6 ee%. They could be recollected by simply elevating the temperature with a high yield of around 95% and reused without compromising the stereoselectivity and stability.