Comparison of Saliva Pcr Assay Versus Rapid Culture for Detection of Congenital Cytomegalovirus Infection. Issue 5 (May 2015)

• Record Type: Journal Article
• Authors: Pinninti, Swetha G.; Ross, Shannon A.; Shimamura, Masako; Novak, Zdenek; Palmer, April L.; Ahmed, Amina; Tolan, Robert W.; Bernstein, David I.; Michaels, Marian G.; Sánchez, Pablo J.; Fowler, Karen B.; Boppana, Suresh B.
• Is Part Of: Pediatric infectious disease journal. Volume 34:Issue 5(2015)
• Publication Date: 2015-05
• Subjects: congenital CMV -- hearing loss -- late-onset -- saliva; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000000609
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : As part of the CMV and Hearing Multicenter Screening (CHIMES) study, 72, 239 newborns were screened for cytomegalovirus by rapid culture and real-time PCR of saliva samples. Of the 266 infants with congenital cytomegalovirus infection, discordance between rapid culture and PCR was observed in 14 children, and 13 were identified only by PCR, demonstrating the superiority of the PCR assay.