Iron Oxide Nanoparticles: Innovative Tool in Cancer Diagnosis and Therapy. Issue 5 (4th December 2017)

• Record Type: Journal Article
• Authors: Martinkova, Pavla; Brtnicky, Martin; Kynicky, Jindrich; Pohanka, Miroslav
• Is Part Of: Advanced healthcare materials. Volume 7:Issue 5(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-12-04
• Subjects: cancer -- hyperthermia -- iron oxide nanoparticles -- magnetic resonance imagining -- targeted drug delivery; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201700932
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract: Although cancer is one of the most dangerous and the second most lethal disease in the world, current therapy including surgery, chemotherapy, radiotherapy, etc., is highly insufficient not in the view of therapy success rate or the amount of side effects. Accordingly, procedures with better outcomes are highly desirable. Iron oxide nanoparticles (IONPs) present an innovative tool—ideal for innovation and implementation into practice. This review is focused on summarizing some well‐known facts about pharmacokinetics, toxicity, and the types of IONPs, and furthermore, provides a survey of their use in cancer diagnosis and therapy. Abstract : Cancer represents one of the most dangerous diseases of present days and research for the most innovative and noninvasive diagnostic, and therapeutic methods is a contemporary issue since the current medical approaches are not complying with the development of the disease. Magnetic nanoparticles fulfill a demanding need in this clinical area and should be integrated into practice.