Hybrid Materials: Flexible Modulation of CO‐Release Using Various Nuclearity of Metal Carbonyl Clusters on Graphene Oxide for Stroke Remediation (Adv. Healthcare Mater. 5/2018). Issue 5 (7th March 2018) - Tan, Mein Jin
Abstract : A facile CO‐release material for in‐situ vasodilation as a treatment for stroke‐related vascular diseases is developed by K.V. Kong, L.D. Liao and co‐workers in article number1701113 . Utilizing the size dependent adsorption properties of ruthenium carbonyl clusters (Ru‐CO) onto graphene oxide (GO), the rate and amount of formation of the CO release‐active Ru II (CO)2 species can be modulated by a simple mixing procedure. Further modulation of thermal and CO release properties can be achieved via a hybridization of medium‐ and high‐ nuclearity of Ru‐CO clusters that can provide photo‐thermal response for in‐situ CO release in a cortical photo‐thrombotic ischemia rat model.