Denonvilliers' fascia in men: a sheet plastination and confocal microscopy study of the prerectal space and the presence of an optimal anterior plane when mobilizing the rectum for cancer. (1st March 2018)

• Record Type: Journal Article
• Authors: Xu, Z.; Chapuis, P. H.; Bokey, L.; Zhang, M.
• Is Part Of: Colorectal disease. Volume 20:Number 3(2018)
• Page Start: 236
• Page End: 242
• Publication Date: 2018-03-01
• Subjects: Sheet plastination -- Denonvilliers' fascia -- prerectal space -- surgical plane -- rectal cancer; Colon (Anatomy) -- Diseases -- Periodicals; Rectum -- Diseases -- Periodicals; 616.34
• DOI: 10.1111/codi.13906
• Languages: English
• ISSNs: 1462-8910

Abstract

Abstract: Aim: The aim of this study was to investigate the detailed, in situ, morphology of Denonvilliers' fascia (DVF) in cadavers using sheet plastination and confocal microscopy and to review and describe the optimal anterior plane for mobilization of the distal rectum. Method: Six male cadavers (age range 46–87 years) were prepared as six sets of transverse (× 2), coronal (× 1) and sagittal (× 3) plastinated sections which were examined under a confocal laser scanning microscope. Results: In this study a consistent space between the anterior rectal wall and the posterior surface of the prostate and seminal vesicles above the level of the perineal body was termed the prerectal space. Within that prerectal space we identified fibres which take their origin from the external urethral sphincter (EUS), together with others from the longitudinal rectal muscle (LRM) and the connective tissue sheaths of neurovascular bundles. Neither the EUS‐ nor the LRM‐originated fibres were continuous with the endopelvic fascia; they were interposed laterally and cranially by multiple neurovascular bundles. Further, our results suggest that the peritoneum does not descend deep within the prerectal space. Conclusion: This study reveals the undisturbed, in situ, structural detail of membrane‐like structures in the prerectal space and confirms that the optimal plane for anterolateral mobilization of the rectum is posterior to the multilayered Denonvilliers' fascia.