Evidence for an antagonistic interaction between reward and punishment sensitivity on striatal activity: A verification of the Joint Subsystems Hypothesis. (February 2015)

• Record Type: Journal Article
• Authors: Mortensen, Jørgen Assar; Lehn, Hanne; Evensmoen, Hallvard Røe; Håberg, Asta K.
• Is Part Of: Personality and individual differences. Volume 74(2015)
• Page Start: 214
• Page End: 219
• Publication Date: 2015-02
• Subjects: fMRI -- Joint Subsystems Hypothesis -- Reward sensitivity -- Striatum -- Dopamine -- Reinforcement Sensitivity Theory; Personality -- Periodicals; Individuality -- Periodicals; Individuality -- Periodicals; Personality Development -- Periodicals; Personnalité -- Périodiques; Individualité -- Périodiques; 155.205
• DOI: 10.1016/j.paid.2014.10.023
• Languages: English
• ISSNs: 0191-8869

Abstract

Highlights: Trait reward sensitivity predicts increased activation of the ventral striatum. Low trait avoidance enhances ventral striatal activity and impulsive behavior. Antagonist effects between traits affect striatal activity and behavior. The results support the Joint Subsystems Hypothesis. Abstract: The Reinforcement Sensitivity Theory proposes that the Behavioral Approach System (BAS) comprises dopaminergic brain regions and underpins reward sensitivity causing impulsivity. It has been shown in a supraliminal priming task that highly reward sensitive subjects have a larger reaction time (RT) priming effect and make more commission errors to prime-incongruent targets. We adapted a similar task to event-related fMRI and hypothesized that (1) high reward sensitivity is associated with increased activation in dopaminergic brain regions, the ventral striatum in particular, (2) that BAS related personality traits predict impulsivity and (3) that the BAS effects are larger after adjusting for the interactive influence of trait avoidance, as predicted by the Joint Subsystems Hypothesis. Fourteen healthy females participated in the fMRI experiment and were scored on sensitivity to reward (SR) and trait avoidance, i.e., sensitivity to punishment (SP) and neuroticism (N). SR scores were adjusted by SP and N scores. As hypothesized, adjusted SR scores predicted, more than SR scores alone, activity in the ventral striatum (left caudate nucleus and nucleus accumbens). SR+/ SP− scores predicted increased impulsiveness, i.e., a right side RT priming effect. These results support the Joint Subsystems Hypothesis.