Centralized Pan-Middle East Survey on the Undertreatment of Hypercholesterolemia: Results From the CEPHEUS Study in Arabian Gulf Countries. (November 2014)

• Record Type: Journal Article
• Authors: Arafah, Mohamed; Al-Hinai, Ali T.; Mahmeed, Wael Al; Al-Rasadi, Khalid; Tamimi, Omer Al; Herz, Shorook Al; Anazi, Faisal Al; Nemer, Khalid Al; Metwally, Othman; Alkhadra, Akram; Fakhry, Mohammed; Elghetany, Hossam; Medani, Abdel Razak; Yusufali, Afzal Hussein; Jassim, Obaid Al; Hallaq, Omar Al; Baslaib, Fahad Omar Ahmed S.; Alawadhi, Mahmoud; Amin, Haitham; Al-Hashmi, Khamis; Shehab, Abdullah
• Is Part Of: Angiology. Volume 65:Number 10(2014)
• Page Start: 919
• Page End: 926
• Publication Date: 2014-11
• Subjects: hypercholesterolemia -- lipids -- low-density lipoprotein -- cardiovascular -- coronary -- guidelines -- Arabian Gulf countries; Blood-vessels -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.13005
• DOI: 10.1177/0003319713512414
• Languages: English
• ISSNs: 0003-3197

Abstract

The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.