A Quinazolinone based fluorescent chemosensor for selective detection of Fe(III) in aqueous media: Applications to pharmaceutical and environmental analysis. Issue 1 (2nd January 2018)

• Record Type: Journal Article
• Authors: Dongare, Pravin R.; Gore, Anil H.; Kondekar, Uttam R.; Kolekar, Govind B.; Ajalkar, Balu D.
• Is Part Of: Inorganic and nano-metal chemistry. Volume 48:Issue 1(2018)
• Page Start: 49
• Page End: 56
• Publication Date: 2018-01-02
• Subjects: Quinazolinone -- Fluorescent chemosensor -- Fe3+ ion -- Aqueous media -- DFT; Inorganic compounds -- Synthesis -- Periodicals; Nanostructured materials -- Periodicals; Reactivity (Chemistry) -- Periodicals; Inorganic compounds -- Synthesis; Nanostructured materials; Reactivity (Chemistry); Periodicals; 546
• DOI: 10.1080/24701556.2017.1357631
• Languages: English
• ISSNs: 2470-1556

Abstract

ABSTRACT: A Quinazolinone based chemosensor 2-(1, 3-thiazol-2-yl)-2, 3-dihydroquinazolin-4(1 H )-one (1 ) has been synthesized, that exhibits high sensitivity and selectivity for Fe 3+ over other environmentally and biologically relevant metal ions by the changes in fluorescence properties and reversible with the addition of EDTA. Under the optimized conditions, Stern-Volmer plot gives a good relationship between chemosensor1 and Fe 3+ with detection limit 0.0366 µg.mL −1 . The binding mode of1 toward Fe 3+ has been investigated by Job's plot, Benesi-Hildebrand plot, FTIR spectra measurements and theoretically supported by DFT calculations. Moreover, the sensor was successfully `applied for quantitative determination of Fe 3+ ions in pharmaceutical and water sample.