Influence of medical nutrition therapy on borderline glucose intolerance in pregnant Taiwanese women. (2nd April 2016)

• Record Type: Journal Article
• Authors: Ho, Tsung-Chin; Yan, Yuan-Horng; Lu, Mei-Chun; Yu, Cheng-Wei; Wang, Panchalli
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 29:Number 7(2016)
• Page Start: 1181
• Page End: 1186
• Publication Date: 2016-04-02
• Subjects: Borderline glucose intolerance -- excessive weight gain -- gestational diabetes mellitus -- medical nutrition therapy -- pregnancy outcome; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.3109/14767058.2015.1039508
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective : To investigate the influence of medical nutrition therapy (MNT) on borderline glucose intolerance (BGI) in pregnant Taiwanese women. Methods : A total of 5194 singleton pregnant women were enrolled in this prospective, non-randomized study. The participants were subjected to the 50 g 1-h glucose challenge test (GCT) and 100 g 3-h oral glucose tolerance test (OGTT) to screening gestational diabetes mellitus (GDM). BGI was defined as a positive GCT and normal OGTT results. GDM was defined as a positive GCT and abnormal OGTT results. The women were categorized into the following groups: (1) GCT-negative, n = 3881; (2) BGI with MNT, n = 273; (3) BGI without MNT, n = 712; and (4) GDM, n = 328. Multiple logistic analyses were used to estimate the risks of pregnancy outcomes. Results : The odds ratios (95% confidence interval) for total cesareans, third- or fourth-degree perineal lacerations, gestational hypertension or preeclampsia and macrosomia were 1.24 (1.04–1.49), 1.55 (1.06–1.28), 1.78 (1.21–2.61) and 2.50 (1.28–4.91) in the BGI without MNT group compared to the GCT-negative group. There was no difference between BGI with MNT and GCT-negative groups. Conclusions : Women with BGI who did not receive MNT had increased risks of adverse pregnancy outcomes, whereas who received MNT had no different risk with GCT-negative women.