Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial. (1st October 2015)

• Record Type: Journal Article
• Authors: Balkus, Jennifer E.; Nair, Gonasagrie; Montgomery, Elizabeth T.; Mishra, Anu; Palanee-Phillips, Thesla; Ramjee, Gita; Panchia, Ravindre; Selepe, Pearl; Richardson, Barbra A.; Chirenje, Zvavahera M.; Marrazzo, Jeanne M.
• Is Part Of: Journal of acquired immune deficiency syndromes. Volume 70:Number 2(2015)
• Publication Date: 2015-10-01
• Subjects: HIV-1 in women -- age-disparate relationships -- male partner -- South Africa -- sexual behavior; AIDS (Disease) -- Periodicals; Acquired Immunodeficiency Syndrome -- Periodicals; AIDS (Disease); Periodicals; 616.9792005
• DOI: 10.1097/QAI.0000000000000715
• Languages: English
• ISSNs: 1525-4135

Abstract

Abstract : Abstract: A recent analysis from South Africa reported no association between age-disparate relationships and HIV-1 acquisition. We assessed the association between male partner age and HIV-1 acquisition among South African women participating in the VOICE trial. Of 4077 women enrolled, 3789 had complete data; 26% and 5% reported having a partner >5 and >10 years older at enrollment, respectively. Reporting a partner >5 years older (hazard ratio = 1.00; 95% confidence interval: 0.74 to 1.35) or >10 older (hazard ratio = 0.92; 95% confidence interval: 0.49 to 1.74) was not associated with HIV-1 acquisition. These data corroborate recent reports and may suggest a shift in local epidemiology of heterosexual HIV-1 transmission.