An integrative neural model of social perception, action observation, and theory of mind. (April 2015)

• Record Type: Journal Article
• Authors: Yang, Daniel Y.-J.; Rosenblau, Gabriela; Keifer, Cara; Pelphrey, Kevin A.
• Is Part Of: Neuroscience and biobehavioral reviews. Volume 51(2015:Apr.)
• Page Start: 263
• Page End: 275
• Publication Date: 2015-04
• Subjects: Social neuroscience -- Neural systems -- Social information processing -- Social perception -- Action observation -- Mirror system -- Imitation -- Theory of mind -- Mentalizing -- Posterior superior temporal sulcus -- Functional connectivity -- Autism spectrum disorder -- Psychiatric disorders; Psychophysiology -- Periodicals; Human behavior -- Periodicals; Animal behavior -- Periodicals; Neurology -- Periodicals; Behavior -- Periodicals; Ethology -- Periodicals; Neurology -- Periodicals; Psychophysiologie -- Périodiques; Comportement humain -- Périodiques; Animaux -- Mœurs et comportement -- Périodiques; Neurologie -- Périodiques; Animal behavior; Human behavior; Neurology; Psychophysiology; Periodicals; Electronic journals; 573.8
• DOI: 10.1016/j.neubiorev.2015.01.020
• Languages: English
• ISSNs: 0149-7634

Abstract

Highlights: Three major neural systems underlying social information processing are integrated. They are systems for social perception, action observation, and theory of mind. The posterior superior temporal sulcus (pSTS) is uniquely shared across all systems. The pSTS is functionally connected to all other key regions in the three systems. The model has important implications for psychiatric disorders such as autism. Abstract: In the field of social neuroscience, major branches of research have been instrumental in describing independent components of typical and aberrant social information processing, but the field as a whole lacks a comprehensive model that integrates different branches. We review existing research related to the neural basis of three key neural systems underlying social information processing: social perception, action observation, and theory of mind. We propose an integrative model that unites these three processes and highlights the posterior superior temporal sulcus (pSTS), which plays a central role in all three systems. Furthermore, we integrate these neural systems with the dual system account of implicit and explicit social information processing. Large-scale meta-analyses based on Neurosynth confirmed that the pSTS is at the intersection of the three neural systems. Resting-state functional connectivity analysis with 1000 subjects confirmed that the pSTS is connected to all other regions in these systems. The findings presented in this review are specifically relevant for psychiatric research especially disorders characterized by social deficits such as autism spectrum disorder.