Holmes and Horrax (1919) revisited: Impaired binocular fusion as a cause of "flat vision" after right parietal brain damage – A case study. (March 2015)

• Record Type: Journal Article
• Authors: Schaadt, Anna-Katharina; Brandt, Stephan A.; Kraft, Antje; Kerkhoff, Georg
• Is Part Of: Neuropsychologia. Volume 69(2015)
• Page Start: 31
• Page End: 38
• Publication Date: 2015-03
• Subjects: FU follow up -- SD standard deviation -- Mdn median -- IQR interquartile range; Binocular vision -- Stereopsis -- Fusion -- Depth perception -- Parietal lobe -- V6/V6A; Neuropsychology -- Periodicals; Neurology -- Periodicals; Psychophysiology -- Periodicals; Neuropsychologie -- Périodiques; Neuropsychology; Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.neuropsychologia.2015.01.029
• Languages: English
• ISSNs: 0028-3932

Abstract

Abstract: The complete loss of binocular depth perception ("flat vision") was first thoroughly described byHolmes and Horrax (1919), and has been occasionally reported thereafter in patients with bilateral posterior-parietal lesions. Though partial spontaneous recovery occurred in some cases, the precise cause(s) of this condition remained obscure for almost a century. Here, we describe a unique patient (EH) with a large right-sided occipito-parietal hemorrhage showing a complete loss of visual depth perception for several months post-stroke. EH could well simultaneously describe multiple visual objects – hence did not show simultanagnosia – but at the same time was completely unable to estimate their distance from him. In every 3-D visual scene objects appeared equidistant to him, thus experiencing a total loss of depth perception ("flat vision"). Neurovisual assessments revealed normal functions of the eyes. EH showed bilateral lower field loss and a severely impaired binocular convergent fusion, but preserved stereopsis. Perceptual re-training of binocular fusion resulted in a progressive and finally complete recovery of objective binocular fusion values and subjective binocular depth perception in a far-to-near-space, gradient-like manner. In parallel, visual depth estimation of relative distances improved, whereas stereopsis remained unchanged. Our results show that a complete loss of 3-D depth perception can result from an isolated impairment in binocular fusion. On a neuroanatomical level, this connection could be explained by a selective lesion of area V6/V6A in the medial occipito-parietal cortex that has been associated with the integration of visual space coordinates and sustained eye-positions into a cyclopean visual 3-D percept. Highlights: "Flat vision": Complete loss of binocular 3-dimensional depth perception. First described in 1919, its causes remained unknown. Patient EH: "flat vision" and binocular fusion impairment after V6/V6A lesion Repetitive dichoptic training led to a full reinstatement of 3-D depth perception. "Flat vision" can result from insufficient binocular fusion.