Extensive cerebral white matter involvement in a patient with NMO spectrum disorder. (September 2014)

• Record Type: Journal Article
• Authors: Ayrignac, Xavier; Dalière, Clarisse Carra; Nerrant, Elodie; Vincent, Thierry; De Seze, Jérôme; Labauge, Pierre
• Is Part Of: Multiple sclerosis. Volume 20:Number 10(2014)
• Page Start: 1401
• Page End: 1403
• Publication Date: 2014-09
• Subjects: Neuromyelitis Optica -- Devic's syndrome -- white matter disease; Central nervous system -- Diseases -- Periodicals; Myelin sheath -- Diseases -- Periodicals; Inflammation -- Periodicals; Multiple sclerosis -- Periodicals; Central Nervous System Diseases -- Periodicals; Demyelinating Diseases -- Periodicals; Inflammation -- Periodicals; Multiple Sclerosis -- Periodicals; Système nerveux central -- Maladies -- Périodiques; Gaine de myéline -- Maladies -- Périodiques; Inflammation (Pathologie) -- Périodiques; Sclérose en plaques -- Périodiques; Electronic journals; 616.834005
• DOI: 10.1177/1352458514536253
• Languages: English
• ISSNs: 1352-4585

Abstract

Abnormal brain MRI has been described in up to 60% of patients with NMO patients. However, white matter T2 hyperintensities have been rarely observed. We report the case of a 49-year-old woman with long-lasting neuromyelitis optica (NMO) spectrum disorder and diffuse cerebral white matter T2-weighted hyperintensities. Our case suggests that some NMO patients can progressively develop l extensive cerebral involvement.