Amniotic fluid "sludge" is an independent risk factor for preterm delivery. (2nd January 2016)

• Record Type: Journal Article
• Authors: Hatanaka, Alan Roberto; Mattar, Rosiane; Kawanami, Tatiana Emy Nishimoto; França, Marcelo Santucci; Rolo, Liliam Cristine; Nomura, Roseli Mieko Yamamoto; Araujo Júnior, Edward; Nardozza, Luciano Marcondes Machado; Moron, Antonio Fernandes
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 29:Number 1(2016)
• Page Start: 120
• Page End: 125
• Publication Date: 2016-01-02
• Subjects: Amniotic fluid "sludge" -- cervical length measurement -- chorioamnionitis -- inflammation -- premature birth -- ultrasonography; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.3109/14767058.2014.989202
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective : To determine the prevalence and the clinical significance of amniotic fluid "sludge" (AFS) in asymptomatic patients at low and high risk for spontaneous preterm delivery. Method : A prospective cohort study was conducted on 195 singleton pregnancies at low or high risk for preterm birth (PTB) between the 16th and 26th weeks. Cervical length (CL) <25 mm and the presence of AFS were evaluated. The risk for preterm delivery before 28, 32, 35 and 37 weeks were determined according to the presence of AFS, CL < 25 mm and history of high risk for PTB. Stepwise logistic regression was performed to compare variables. Results : AFS was an independent risk factor for PTB < 35 weeks (OR: 3.08, 95% CI: 1.13–8.34, p = 0.027) but not for PTB < 28, 32 and 37 weeks. CL < 25 mm was an independent risk factor for PTB < 28, 32 and 35 but not for PTB < 37 weeks. High risk for PTB was not found as an independent risk factor for PTB. Conclusion : AFS is an independent risk factor for PTB before 35 weeks.