Optimal blood pressure in patients with peripheral artery disease following endovascular therapy. (2nd January 2016)

• Record Type: Journal Article
• Authors: Sasaki, Haruki; Ura, Nobuyuki; Hata, Shinya; Moniwa, Norihito; Hasegawa, Koichi; Takizawa, Hideki; Tanaka, Shigemichi
• Is Part Of: Blood pressure. Volume 25:Number 1(2016)
• Page Start: 36
• Page End: 43
• Publication Date: 2016-01-02
• Subjects: Endovascular procedures -- metformin -- peripheral artery disease -- restenosis; Blood pressure -- Periodicals; Hypertension -- Periodicals; Hypertension -- Periodicals; Blood Pressure -- Periodicals; 612.14
• DOI: 10.3109/08037051.2016.1093717
• Languages: English
• ISSNs: 0803-7051

Abstract

Abstract: This study examined the associations between blood pressure (BP) and event incidence to define optimal BP after endovascular therapy (EVT) in patients who underwent EVT. BP was monitored every 6 months for 5 years, and the patients were divided into two groups by average BP: ≥ 140/90 mmHg and < 140/90 mmHg. The association of BP with several events was examined. Although no significant differences in total mortality were observed between the groups, restenosis rates were significantly higher among patients who did not achieve target BP (36.2%) than among those who did (18.2%) ( p < 0.01). The percentage of patients with glycosylated haemoglobin > 7.0% was significantly higher among those who did not achieve target BP in the restenosis group (42.9%) than in the other group (10.8%) ( p < 0.01). In the restenosis group, there was a significantly higher percentage of patients taking metformin ( p < 0.01) than in the other group. Metformin seemed to be administered to patients with more severe diabetes mellitus. In conclusion, it is important to manage hypertension and diabetes to prevent restenosis after EVT.