Acute humoral rejection in an infant without risk factors after heart transplantation. Issue 2 (4th February 2018)

• Record Type: Journal Article
• Authors: Binsalamah, Ziyad M.; Marcano, Juan; Zea‐Vera, Rodrigo; Tunuguntla, Hari; Kearney, Debra L.; Heinle, Jeffrey S.; Fraser, Charles D.; Mery, Carlos M.
• Is Part Of: Journal of cardiac surgery. Volume 33:Issue 2(2018)
• Page Start: 126
• Page End: 128
• Publication Date: 2018-02-04
• Subjects: dilated cardiomyopathy -- heart transplantation -- humoral rejection; Heart -- Surgery -- Periodicals; 617.412005
• DOI: 10.1111/jocs.13532
• Languages: English
• ISSNs: 0886-0440

Abstract

Abstract: Graft rejection is the most common factor that limits graft survival after transplantation. During infancy, the humoral immune system is partially suppressed and humoral rejection of a cardiac allograft has not been reported in the absence of risk factors such as prior transplantation, blood transfusions, ventricular assist devices, and elevation of panel reactive antibodies. We present a case of an infant with dilated cardiomyopathy who developed multiple episodes of acute humoral rejection after heart transplantation in the absence of risk factors.